Abraxane (Albumin-bound Paclitaxel) Drug Information: Overdosage and Contraindications

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May 21, 2012

Abraxane

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Breast cancer facts

Breast cancer is the most common cancer among American women.
One in every eight women in the United States develops breast cancer.
There are many types of breast cancer that differ in their capability of spreading (metastasize) to other body tissues.
The causes of breast cancer are not yet fully known although a number of risk factors have been identified.
There are many different types of breast cancer.
Breast cancer is diagnosed with physician and self-examination of the breasts, mammography, ultrasound testing, and biopsy.
Treatment of breast cancer depends on the type of cancer and its stage (the extent of spread in the body).

According to the American Cancer society:

Over 200,000 new cases of invasive breast cancer are diagnosed each year.
Nearly 40,000 women will die of breast cancer in 2011.
There are over 2...

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OVERDOSE

There is no known antidote for ABRAXANE overdosage. The primary anticipated complications of overdosage would consist of bone marrow suppression, sensory neurotoxicity, and mucositis.

CONTRAINDICATIONS

ABRAXANE should not be used in patients who have baseline neutrophil counts of < 1,500 cells/mm³. Patients who experience a severe hypersensitivity reaction to ABRAXANE should not be rechallenged with the drug.

Last reviewed on RxList: 3/19/2012
This monograph has been modified to include the generic and brand name in many instances.