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Brand Names: Abraxane

Generic Name: paclitaxel protein-bound (Pronunciation: PAK li TAX el PRO teen-bound)

• What is paclitaxel protein-bound (Abraxane)?
• What are the possible side effects of paclitaxel protein-bound (Abraxane)?
• What is the most important information I should know about paclitaxel protein-bound (Abraxane)?
• What should I discuss with my healthcare provider before taking paclitaxel protein-bound (Abraxane)?
• How should I use paclitaxel protein-bound (Abraxane)?
• What happens if I miss a dose (Abraxane)?
• What happens if I overdose (Abraxane)?
• What should I avoid while using paclitaxel protein-bound (Abraxane)?
• What other drugs will affect paclitaxel protein-bound (Abraxane)?
• Where can I get more information?

What is paclitaxel protein-bound (Abraxane)?

Paclitaxel protein-bound is a cancer (antineoplastic) medication. Paclitaxel protein-bound interferes with the growth of cancer cells and slows their growth and spread in the body.

Paclitaxel protein-bound is used in the treatment breast cancer.

Paclitaxel protein-bound may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of paclitaxel protein-bound (Abraxane)?

If you experience any of the following serious side effects from paclitaxel protein-bound, seek emergency medical attention or contact your doctor immediately:

• an allergic reaction (including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
• decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection);
• liver damage (abdominal pain, yellowing of the skin or eyes); or
• severe nausea, vomiting, or diarrhea;
• numbness or tingling; or
• irregular heartbeats.

Other, less serious side effects may be more likely to occur. Continue taking paclitaxel protein-bound and talk to your doctor if you experience:

• tissue or vein reactions near the site of administration;
• low red blood cell count;
• joint or muscle pain;
• sores in the mouth;
• hair loss; or
• mild to moderate nausea, vomiting, diarrhea, or loss of appetite.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about paclitaxel protein-bound (Abraxane)?

Paclitaxel protein-bound should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Serious side effects have been reported with the use of paclitaxel protein-bound including: allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection); numbness or tingling; irregular heartbeats; and others. Talk to your doctor about the possible side effects from treatment with paclitaxel protein-bound.