ACANYA Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) is a combination product with two active ingredients in an aqueous gel formulation. Clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.

The chemical name for clindamycin phosphate is Methyl 7-chloro­6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1­thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate). The structural formula for clindamycin phosphate is represented below:

Clindamycin phosphate:

Molecular Formula: C₁₈H₃₄ClN₂O₈PS Molecular Weight: 504.97

Benzoyl peroxide is an antibacterial and keratolytic agent. The structural formula for benzoyl peroxide is represented below:

Benzoyl peroxide:

Molecular Formula: C₁₄H₁₀O₄ Molecular Weight: 242.23

ACANYA Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) contains the following inactive ingredients: purified water, carbomer 980, propylene glycol, and potassium hydroxide. Each gram of ACANYA Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) contains 1.2% of clindamycin phosphate which is equivalent to 1% clindamycin.

Last reviewed on RxList: 7/20/2010
This monograph has been modified to include the generic and brand name in many instances.