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Angioedema, including laryngeal edema, can occur with treatment with ACE inhibitors, especially following the first dose. Patients receiving ACCURETIC should be told to report immediately any signs or symptoms suggesting angioedema (swelling of face, eyes, lips, or tongue, or difficulty in breathing) and to take no more drug until after consulting with the prescribing physician.
Female patients of childbearing age should be told about the consequences of exposure to ACCURETIC during pregnancy. Discuss treatment options with women planning to become pregnant. Patients should be asked to report pregnancies to their physicians as soon as possible.
A patient receiving ACCURETIC should be cautioned that lightheadedness can occur, especially during the first days of therapy, and that it should be reported to the prescribing physician. The patient should be told that if syncope occurs, ACCURETIC should be discontinued until the physician has been consulted.
All patients should be cautioned that inadequate fluid intake, excessive perspiration, diarrhea, or vomiting can lead to an excessive fall in blood pressure because of reduction in fluid volume, with the same consequences of lightheadedness and possible syncope.
Patients planning to undergo major surgery and/ or general or spinal anesthesia should be told to inform their physicians that they are taking an ACE inhibitor.
A patient receiving ACCURETIC should be told not to use potassium supplements or salt substitutes containing potassium without consulting the prescribing physician.
NOTE: As with many other drugs, certain advice to patients being treated with quinapril is warranted. This information is intended to aid in the safe and effective use of this medication. It is not a disclosure of all possible adverse or intended effects.
The hydrochlorothiazide component of ACCURETIC may decrease serum PBI levels without signs of thyroid disturbance.
Therapy with ACCURETIC should be interrupted for a few days before carrying out tests of parathyroid function.
Last reviewed on RxList: 2/19/2015
This monograph has been modified to include the generic and brand name in many instances.
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