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Acetadote

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Acetadote

ACETADOTE
(acetylcysteine) for Injection

DRUG DESCRIPTION

Acetylcysteine injection is an intravenous antidote for the treatment of acetaminophen overdose. Acetylcysteine is the nonproprietary name for the N-acetyl derivative of the naturally occurring amino acid, L-cysteine (N-acetyl-Lcysteine,). The compound is a white crystalline powder, which melts in the range of 104° to 110°C and has a very slight odor. The molecular formula of the compound is C5H9NO3S, and its molecular weight is 163.2. Acetylcysteine has the following structural formula:

ACETADOTE (acetylcysteine) Structural Formula Illustration

Acetadote is supplied as a sterile solution in vials containing 20% w/v (200 mg/mL) acetylcysteine. The pH of the solution ranges from 6.0 to 7.5. Acetadote contains the following inactive ingredients: sodium hydroxide (used for pH adjustment), and Sterile Water for Injection, USP.

What are the precautions when taking acetylcysteine injection (Acetadote)?

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Read All Potential Precautions of Acetadote »

Last reviewed on RxList: 6/24/2013
This monograph has been modified to include the generic and brand name in many instances.

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