"SILVER SPRING, MD â€” The US Food and Drug Administration (FDA) issued a MedWatch safety alert today regarding premature battery depletion in some implantable cardioverter defibrillators (ICDs) and cardiac-resynchronization-therapy defibrillators ("...
Adverse reactions common to all sulfonamide derivatives may occur: anaphylaxis, fever, rash (including erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis) crystalluria, renal calculus, bone marrow depression, thrombocytopenic purpura, hemolytic anemia, leukopenia, pancytopenia and agranulocytosis. Precaution is advised for early detection of such reactions and the drug should be discontinued and appropriate therapy instituted.
Gradual ascent is desirable to try to avoid acute mountain sickness. If rapid ascent is undertaken and acetaZOLAMIDE is used, it should be noted that such use does not obviate the need for prompt descent if severe forms of high altitude sickness occur. i.e., high altitude pulmonary edema (HAPE) or highaltitude cerebral edema.
Last reviewed on RxList: 10/7/2016
This monograph has been modified to include the generic and brand name in many instances.
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