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Acetazolamide Injection

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Acetazolamide Injection

Acetazolamide for Injection USP
For Intravenous Use.

DRUG DESCRIPTION

Acetazolamide, an inhibitor of the enzyme carbonic anhydrase, is a white to faintly yellowish white crystalline, odorless powder, weakly acidic, very slightly soluble in water and slightly soluble in alcohol. The chemical name for acetazolamide is N-(5-Sulfamoyl-1,3,4-thiadiazol-2yl)-acetamide and has the following structural formula:

Acetazolamide structural formula illustration

M.W. 222.24       C4H6N4O3S2

Acetazolamide is available for intravenous use, and is supplied as a sterile powder requiring reconstitution. Each vial contains acetazolamide sodium equivalent to 500 mg of acetazolamide. The bulk solution is adjusted to pH 9.6 using sodium hydroxide and, if necessary, hydrochloric acid prior to lyophilization.

Last reviewed on RxList: 6/14/2007
This monograph has been modified to include the generic and brand name in many instances.

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