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Antacids are a class of drugs used to treat conditions caused by the acid that is produced by the stomach. The stomach naturally secretes an acid called hydrochloric acid that helps to break down proteins. This acid causes the contents of the stomach to be acidic in nature, with a pH level of 2 or 3. (pH levels are a measure of acidity in the stomach: the lower the number, the greater the acidity.) The stomach, duodenum, and esophagus are protected from acid by several protective mechanisms. When there is too much acid or protective mechanisms are inadequate, the lining of the stomach, duodenum or esophagus may become damaged by the acid, giving rise to various gastrointestinal symptoms such as abdominal pain, heartburn (due to gastroesophageal reflux disease or GERD), and other gastro-esophageal symptoms.
Antacids reduce acidity by neutralizing (counteracting) acid, reducing the acidity in the stomac...
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Medical Editor: Charles Patrick Davis, MD, PhD
Aciphex (rabeprazole sodium) is a proton pump inhibitor (PPI) to reduce stomach acid and is used for the treatment of gastroesophageal reflux disease (GERD), duodenal ulcers, and in combination with antibiotics, Helicobacter bacterial infections in the stomach. Aciphex is available as generic termed rabeprazole sodium. Common side effects of Aciphex may include rash or itching, upset stomach and diarrhea, gas, sore throat, headache, and insomnia.
Aciphex is available in 20 mg strength enteric-coated tablets. The usual dose of Aciphex is one 20 mg tablet per day for 4 to 8 weeks. Serious side effects of Aciphex may include hepatitis, encephalopathy, dizziness, edema, arthralgia, and muscle pains. Use of Aciphex may increase the availability of warfarin (Coumadin). Use of Aciphex in combination with amoxicillin and clarithromycin does not apparently change the side effects, but the reader is advised to not combine these drugs to treat Helicobacter without informing their doctor because of other side effects possible from the antibiotics. Pregnant women and their doctors need to balance the need vs the potential problems of Aciphex in pregnancy and breastfeeding. Aciphex has been used in pediatric patients, aged 12 and above for GERD treatment; no studies under age 12 are available.
Our Aciphex Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases, and conditions.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
ACIPHEX is indicated for short-term (4 to 8 weeks) treatment in the healing and symptomatic relief of erosive or ulcerative gastroesophageal reflux disease (GERD). For those patients who have not healed after 8 weeks of treatment, an additional 8-week course of ACIPHEX may be considered.
ACIPHEX is indicated for maintaining healing and reduction in relapse rates of heartburn symptoms in patients with erosive or ulcerative gastroesophageal reflux disease (GERD M...
Read the complete drug monograph for Aciphex »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the complete patient information for Aciphex »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before yo...
Read the complete consumer information for Aciphex »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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