April 27, 2017
Recommended Topic Related To:


"The US Food and Drug Administration (FDA) has cleared Omega3-rich fish skin for tissue healing for surgical applications, Kerecis, the Reykjavik, Iceland-based company that developed the product has announced.

Kerecis Omega3 SecureMes"...



(alclometasone dipropionate cream) Cream, 0.05%

(alclometasone dipropionate ointment) Ointment, 0.05%

For Dermatologic Use Only– Not for Ophthalmic Use.


ACLOVATE® (alclometasone dipropionate cream) Cream, 0.05% and ACLOVATE® (alclometasone dipropionate ointment) Ointment, 0.05% contain alclometasone dipropionate (7α-chloro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate), a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti­inflammatory and antipruritic agents.

Chemically, alclometasone dipropionate is C28H37CIO7. It has the following structural formula:

ACLOVATE® (alclometasone dipropionate) Structural Formula Illustration

Alclometasone dipropionate has the molecular weight of 521. It is a white powder insoluble in water, slightly soluble in propylene glycol, and moderately soluble in hexylene glycol.

Each gram of ACLOVATE® Cream contains 0.5 mg of alclometasone dipropionate in a hydrophilic, emollient cream base of propylene glycol, white petrolatum, cetearyl alcohol, glyceryl stearate, PEG 100 stearate, Ceteth-20, monobasic sodium phosphate, chlorocresol, phosphoric acid, and purified water.

Each gram of ACLOVATE® Ointment contains 0.5 mg of alclometasone dipropionate in an ointment base of hexylene glycol, white wax, propylene glycol stearate, and white petrolatum.

What are the possible side effects of alclometasone topical (Aclovate)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing alclometasone topical through your skin, such as:

  • blurred vision, or seeing halos around lights;
  • mood changes;
  • sleep problems (insomnia);
  • weight gain, puffiness in your face; or
  • muscle weakness, feeling tired.


Read All Potential Side Effects and See Pictures of Aclovate »

What are the precautions when taking alclometasone dipropionate cream, ointment (Aclovate)?

Before using alclometasone, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., hydrocortisone, prednisone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, diabetes, immune system problems.

Do not use if there is an infection or sore in the area to be treated.

Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency treatment, or if...

Read All Potential Precautions of Aclovate »

Last reviewed on RxList: 5/23/2011
This monograph has been modified to include the generic and brand name in many instances.

Aclovate - User Reviews

Aclovate User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Aclovate sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Women's Health

Find out what women really need.