"Kids are five times more likely than adults to die from tickborne diseases like Rocky Mountain spotted fever (RMSF). Doctors often avoid prescribing doxycycline, the most effective RMSF treatment for young children, potentially because of the war"...
(doxycycline hyclate) Tablets, USP
ACTICLATE™ (doxycycline hyclate USP) Tablets contain doxycycline hyclate, a broad-spectrum antibacterial synthetically derived from oxytetracycline, in an immediate release formulation for oral administration.
The structural formula for doxycycline hyclate is:
with a molecular formula of (C22H24N2O8, HCl)2• C2H6O• H2O and a molecular weight of 1025.87.
The chemical designation for doxycycline hyclate is:
4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2naphthacenecarboxamide monohydrochloride, compound with ethyl alcohol (2:1), monohydrate.
Doxycycline hyclate is a yellow crystalline powder soluble in water and in solutions of alkali hydroxides and carbonates. Inactive ingredients in the tablet formulation are: microcrystalline cellulose, sodium lauryl sulfate, croscarmellose sodium and magnesium stearate. Film-coating contains: polyvinyl alcohol, titanium dioxide, polyethylene glycol, talc, FD&C Blue #1 (75 mg), FD&C Yellow #6 (75 mg), FD&C Blue #2 (150 mg) and yellow iron oxide (150 mg).
Last reviewed on RxList: 12/21/2016
This monograph has been modified to include the generic and brand name in many instances.
Additional Acticlate Information
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