"The U.S. Food and Drug Administration (FDA) is warning that the type 2 diabetes medicines canagliflozin, dapagliflozin, and empagliflozin may lead to ketoacidosis, a serious condition where the body produces high levels of blood acids called keto"...
Actoplus MET, Actoplus MET XR
Actoplus MET, Actoplus MET XR Patient Information including If I Miss a Dose
In this Article
- What is metformin and pioglitazone (Actoplus MET, Actoplus MET XR)?
- What are the possible side effects of metformin and pioglitazone (Actoplus MET, Actoplus MET XR)?
- What is the most important information I should know about metformin and pioglitazone (Actoplus MET, Actoplus MET XR)?
- What should I discuss with my healthcare provider before taking metformin and pioglitazone (Actoplus MET, Actoplus MET XR)?
- How should I take metformin and pioglitazone (Actoplus MET, Actoplus MET XR)?
- What happens if I miss a dose (Actoplus MET, Actoplus MET XR)?
- What happens if I overdose (Actoplus MET, Actoplus MET XR)?
- What should I avoid while taking metformin and pioglitazone (Actoplus MET, Actoplus MET XR)?
- What other drugs will affect metformin and pioglitazone (Actoplus MET, Actoplus MET XR)?
- Where can I get more information?
What happens if I miss a dose (Actoplus MET, Actoplus MET XR)?
Take the missed dose as soon as you remember (be sure to take the medicine with food). Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Actoplus MET, Actoplus MET XR)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking metformin and pioglitazone (Actoplus MET, Actoplus MET XR)?
Avoid drinking alcohol. It can lower your blood sugar and may increase your risk of lactic acidosis.
What other drugs will affect metformin and pioglitazone (Actoplus MET, Actoplus MET XR)?
Tell your doctor about all other medicines you use, especially:
- bosentan (Tracleer);
- delavirdine (Rescriptor);
- digoxin (Lanoxin);
- gemfibrozil (Lopid);
- morphine (MS Contin, Kadian, Oramorph);
- tolbutamide (Orinase);
- trimethoprim (Proloprim, Primsol, Bactrim, Cotrim, Septra);
- vancomycin (Vancocin, Lyphocin);
- amiloride (Midamor), furosemide (Lasix), or triamterene (Dyrenium);
- cimetidine (Tagamet) or ranitidine (Zantac);
- fluconazole (Diflucan) or ketoconazole (Nizoral);
- nicardipine (Cardene) or nifedipine (Nifedical, Procardia);
- procainamide (Procan, Pronestyl, Procanbid), quinidine (Quin-G), or quinine (Qualaquin);
- rifampin (Rifater, Rifadin, Rifamate) or rifapentine (Priftin);
- a non-steroidal anti-inflammatory drug (NSAID) such as flurbiprofen (Ansaid), ibuprofen (Advil, Motrin), indomethacin (Indocin), mefenamic acid (Ponstel), or piroxicam (Feldene); or
- seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin), phenobarbital (Solfoton), primidone (Mysoline), and others.
You may be more likely to have hyperglycemia (high blood sugar) if you take metformin and pioglitazone with other drugs that can raise blood sugar, such as:
- diuretics (water pills);
- steroids (prednisone and others);
- heart or blood pressure medication (Cartia, Cardizem, Covera, Isoptin, Verelan, and others);
- niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);
- phenothiazines (Compazine and others);
- thyroid medicine (Synthroid and others);
- birth control pills and other hormones;
- seizure medicines (Dilantin and others); and
- diet pills or medicines to treat asthma, colds or allergies.
These lists are not complete and there are many other medicines that can increase or decrease the effects of metformin and pioglitazone on lowering your blood sugar. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about metformin and pioglitazone.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2013 Cerner Multum, Inc. Version: 8.01. Revision date: 7/6/2012.
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Additional Actoplus MET, Actoplus MET XR Information
- Actoplus MET, Actoplus MET XR Drug Interactions Center: pioglitazone-metformin oral
- Actoplus MET, Actoplus MET XR Side Effects Center
- Actoplus MET, Actoplus MET XR Overview including Precautions
- Actoplus MET, Actoplus MET XR FDA Approved Prescribing Information including Dosage
Actoplus MET, Actoplus MET XR - User Reviews
Actoplus MET, Actoplus MET XR User Reviews
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