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During controlled clinical trials, one case of overdose with ACTOS was reported. A male patient took 120 mg per day for four days, then 180 mg per day for seven days. The patient denied any clinical symptoms during this period.

In the event of overdosage, appropriate supportive treatment should be initiated according to the patient's clinical signs and symptoms.


  • Initiation in patients with established NYHA Class III or IV heart failure [see BOXED WARNING].
  • Use in patients with known hypersensitivity to pioglitazone or any other component of ACTOS.
This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 11/25/2013


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