"The U.S. Food and Drug Administration today announced it has begun a safety review of the diabetes drug Actos (pioglitazone), after receiving preliminary results from a long-term observational study designed to evaluate the risk of bladder cancer"...
Actos Patient Information including If I Miss a Dose
In this Article
- What is pioglitazone (Actos)?
- What are the possible side effects of pioglitazone (Actos)?
- What is the most important information I should know about pioglitazone (Actos)?
- What should I discuss with my healthcare provider before taking pioglitazone (Actos)?
- How should I take pioglitazone (Actos)?
- What happens if I miss a dose (Actos)?
- What happens if I overdose (Actos)?
- What should I avoid while taking pioglitazone (Actos)?
- What other drugs will affect pioglitazone (Actos)?
- Where can I get more information?
What happens if I miss a dose (Actos)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Actos)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).
What should I avoid while taking pioglitazone (Actos)?
Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.
What other drugs will affect pioglitazone (Actos)?
Tell your doctor about all other medicines you use, especially:
- bosentan (Tracleer);
- delavirdine (Rescriptor);
- digoxin (Lanoxin);
- gemfibrozil (Lopid);
- midazolam (Versed);
- morphine (MS Contin, Kadian, Oramorph);
- tolbutamide (Orinase);
- trimethoprim (Proloprim, Primsol, Bactrim, Cotrim, Septra);
- vancomycin (Vancocin, Lyphocin);
- amiloride (Midamor), furosemide (Lasix), or triamterene (Dyrenium);
- cimetidine (Tagamet) or ranitidine (Zantac);
- fluconazole (Diflucan) or ketoconazole (Nizoral);
- nicardipine (Cardene) or nifedipine (Nifedical, Procardia);
- procainamide (Procan, Pronestyl, Procanbid), quinidine (Quin-G), or quinine (Qualaquin);
- rifampin (Rifater, Rifadin, Rifamate) or rifapentine (Priftin);
- a non-steroidal anti-inflammatory drug (NSAID) such as celecoxib (Celebrex), flurbiprofen (Ansaid), ibuprofen (Advil, Motrin), indomethacin (Indocin), mefenamic acid (Ponstel), or piroxicam (Feldene); or
- seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin), phenobarbital (Solfoton), primidone (Mysoline), and others.
You may be more likely to have hypoglycemia (low blood sugar) if you take pioglitazone with other drugs that can lower blood sugar, such as:
- probenecid (Benemid);
- some nonsteroidal anti-inflammatory drugs (NSAIDs);
- aspirin or other salicylates (including Pepto-Bismol);
- a blood thinner (warfarin, Coumadin and others);
- heart or blood pressure medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, and others);
- sulfa drugs (Bactrim, Gantanol, Gantrisin, Septra, SMX-TMP, and others);
- a monoamine oxidase inhibitor (MAOI); or
- other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), or rosiglitazone (Avandia).
These lists are not complete and there are many other medicines that can increase or decrease the effects of pioglitazone on lowering your blood sugar. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about pioglitazone.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 12.02. Revision date: 8/30/2011.
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Additional Actos Information
- Actos Drug Interactions Center: pioglitazone oral
- Actos Side Effects Center
- Actos Overview including Precautions
- Actos FDA Approved Prescribing Information including Dosage
Actos - User Reviews
Actos User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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