Acular (Ketorolac Tromethamine) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

Pill Identifier Search

February 9, 2012

Acular

Allergy Drugs: Prescription and OTC »

Allergy medications overview

The arsenal of allergy drugs includes dozens of medications that relieve allergy symptoms when confronted with a trigger known as an allergen. That trigger could be something from a plant, such as pollen, or something from an animal (pet dander, dust mites, cockroaches). Other allergy triggers include certain fragrances or chemical substances.

What causes a person's allergic reaction is highly individual. But the reactions are often universal: swelling and inflammation, especially around the eyes, nose, and throat, usually accompanied by itching.

Some allergy medications work against the effects of histamines, which are released during an allergic reaction. Other medications reduce swelling, affect the immune system, or affect release of other substances associated with allergic reactions.

Many allergy drugs are available without a prescription.

For what conditions are allergy medicatio...

Read the Allergy Drugs: Prescription and OTC article »

« Previous
1
2
3
4
5
6
7
8
9
10
11
12
13
next »

Acular User Reviews >>

Acular

Eye Diseases and Conditions Slideshow Pictures

Pink Eye Slideshow Pictures

Cataracts Slideshow Pictures

font size

ACULAR®
(ketorolac tromethamine) Ophthalmic Solution 0.5% Sterile

DRUG DESCRIPTION

ACULAR® (ketorolac tromethamine ophthalmic solution) is a member of the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAIDs) for ophthalmic use. Its chemical name is (±)-5-benzoyl-2, 3-dihydro-1H pyrrolizine-1-carboxylic acid compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) and it has the following structure:

ACULAR® (ketorolac tromethamine) structural formula illustration

ACULAR® (ketorolac tromethamine) ophthalmic solution is supplied as a sterile isotonic aqueous 0.5% solution, with a pH of 7.4. ACULAR® (ketorolac tromethamine) ophthalmic solution is a racemic mixture of R-(+) and S-(-)- ketorolac tromethamine. Ketorolac tromethamine may exist in three crystal forms. All forms are equally soluble in water. The pKa of ketorolac is 3.5. This white to off-white crystalline substance discolors on prolonged exposure to light. The molecular weight of ketorolac tromethamine is 376.41. The osmolality of ACULAR® (ketorolac tromethamine) ophthalmic solution is 290 mOsmol/kg.

Each mL of ACULAR (ketorolac tromethamine) ® ophthalmic solution contains: Active: ketorolac tromethamine 0.5%. Preservative: benzalkonium chloride 0.01%. Inactives: edetate disodium 0.1%; octoxynol 40; purified water; sodium chloride; hydrochloric acid and/or sodium hydroxide to adjust the pH.

What are the possible side effects of ketorolac ophthalmic (Acular, Acular LS, Acular PF, Acuvail)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

severe burning, stinging, or itching of your eyes;
eye pain, redness, or watering;
vision changes, increased sensitivity to light;
white patches on your eyes; or
crusting or drainage from your...

Read All Potential Side Effects and See Pictures of Acular »

What are the precautions when taking ketorolac tromethamine (Acular)?

Before using ketorolac, tell your doctor or pharmacist if you are allergic to it; or to aspirin, other NSAIDs (e.g., ibuprofen, celecoxib); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, previous eye surgery,...

Read All Potential Precautions of Acular »

Last reviewed on RxList: 4/9/2009
This monograph has been modified to include the generic and brand name in many instances.