ACZONE Gel, 5%, contains dapsone, a sulfone, in an aqueous gel base for topical dermatologic use. ACZONE Gel (dapsone) , 5% is a gritty translucent material with visible drug substance particles. Chemically, dapsone has an empirical formula of C₁₂H₁₂N₂O₂S. It is a white, odorless crystalline powder that has a molecular weight of 248. Dapsone's chemical name is 4,4'-diaminodiphenylsulfone and its structural formula is:

Each gram of ACZONE Gel, 5%, contains 50 mg of dapsone, USP, in a gel of carbomer 980; diethylene glycol monoethyl ether, NF; methylparaben, NF; sodium hydroxide, NF; and purified water, USP.

Last reviewed on RxList: 3/28/2008
This monograph has been modified to include the generic and brand name in many instances.