"What are calcium channel blockers (CCBs) and how do they work?
Calcium channel blockers are drugs that block the entry of calcium into the muscle cells of the heart and arteries.
- The entry of calcium is critical for"...
(nifedipine) Extended Release Tablets
Adalat® CC (nifedipine) is an extended release tablet dosage form of the calcium channel blocker nifedipine. Nifedipine is 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-dimethyl ester, C17H18N2O6, and has the structural formula:
Nifedipine is a yellow crystalline substance, practically insoluble in water but soluble in ethanol. It has a molecular weight of 346.3. Adalat CC (nifedipine) tablets consist of an external coat and an internal core. Both contain nifedipine, the coat as a slow release formulation and the core as a fast release formulation. Adalat CC tablets contain either: 30, 60, or 90 mg of nifedipine for once-a-day oral administration.
Inert ingredients in the formulation are: hydroxypropylcellulose, lactose, corn starch, crospovidone, microcrystalline cellulose, silicon dioxide, and magnesium stearate. The inert ingredients in the film coating for Adalat CC (nifedipine) 30 and 60 are: hypromellose, polyethylene glycol, ferric oxide, and titanium dioxide. The inert ingredients in the film coating for Adalat CC (nifedipine) 90 are: hypromellose, polyethylene glycol and ferric oxide.
What are the possible side effects of nifedipine?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- worsening angina;
- feeling like you might pass out;
- feeling short of breath, swelling in your hands or feet;
- fast or pounding heartbeats;
- numbness or tingly feeling;
- jaundice (yellowing of the skin or eyes); or
- chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill...
What are the precautions when taking nifedipine (Adalat CC)?
Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other calcium channel blockers (e.g., felodipine, amlodipine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., congestive heart failure, aortic stenosis), liver problems, kidney problems, a certain metabolic disorder (porphyria).
Before having surgery, tell your doctor or dentist that you are taking this medication.
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you...
Last reviewed on RxList: 4/14/2011
This monograph has been modified to include the generic and brand name in many instances.
Additional Adalat CC Information
Adalat CC - User Reviews
Adalat CC User Reviews
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