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Peripheral Neuropathy

Advise patients that ADCETRIS can cause a peripheral neuropathy. They should be advised to report to their health care provider any numbness or tingling of the hands or feet or any muscle weakness [see WARNINGS AND PRECAUTIONS].


Advise patients to contact their health care provider if a fever of 100.5°F or greater or other evidence of potential infection such as chills, cough, or pain on urination develops [see WARNINGS AND PRECAUTIONS].

Infusion Reactions

Advise patients to contact their health care provider if they experience signs and symptoms of infusion reactions including fever, chills, rash, or breathing problems within 24 hours of infusion [see WARNINGS AND PRECAUTIONS].


Advise patients to report symptoms that may indicate liver injury, including fatigue, anorexia, right upper abdominal discomfort, dark urine, or jaundice [see WARNINGS AND PRECAUTIONS].

Progressive Multifocal Leukoencephalopathy

Instruct patients receiving ADCETRIS to immediately report if they have any of the following neurological, cognitive, or behavioral signs and symptoms or if anyone close to them notices these signs and symptoms [see BOXED WARNING, WARNINGS AND PRECAUTIONS]:

  • changes in mood or usual behavior
  • confusion, thinking problems, loss of memory
  • changes in vision, speech, or walking
  • decreased strength or weakness on one side of the body


Advise patients to contact their health care provider if they develop severe abdominal pain [see ADVERSE REACTIONS].

Pregnancy and Nursing

ADCETRIS can cause fetal harm. Advise women receiving ADCETRIS to avoid pregnancy. Advise patients to report pregnancy immediately [see WARNINGS AND PRECAUTIONS]. Advise patients to avoid nursing while receiving ADCETRIS [see Use In Specific Populations].

Last reviewed on RxList: 12/11/2014
This monograph has been modified to include the generic and brand name in many instances.

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