"The U.S. Food and Drug Administration today approved Opsumit (macitentan), a new drug to treat adults with pulmonary arterial hypertension (PAH), a chronic, progressive and debilitating disease that can lead to death or the need for lung transpla"...
- Clinician Information:
Adcirca Patient Information including How Should I Take
In this Article
- What is tadalafil (Adcirca)?
- What are the possible side effects of tadalafil (Adcirca)?
- What is the most important information I should know about tadalafil (Adcirca)?
- What should I discuss with my healthcare provider before taking tadalafil (Adcirca)?
- How should I take tadalafil (Adcirca)?
- What happens if I miss a dose (Adcirca)?
- What happens if I overdose (Adcirca)?
- What should I avoid while taking tadalafil (Adcirca)?
- What other drugs will affect tadalafil (Adcirca)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking tadalafil (Adcirca)?
You should not take tadalafil if you are allergic to it.
Tadalafil should not be used together with nitrate medication, such as nitroglycerin (Nitro Dur, Nitrolingual, Nitrostat, Transderm Nitro, and others), isosorbide dinitrate (Dilatrate, Isordil, Isochron), isosorbide mononitrate (Imdur, ISMO, Monoket), or recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking tadalafil with a nitrate medicine for chest pain or heart problems can cause a sudden and serious decrease in blood pressure.
To make sure you can safely take tadalafil, tell your doctor if you have any of these other conditions:
- heart disease or heart rhythm problems;
- a recent heart attack (within the past 90 days);
- a recent history (in the past 6 months) of a stroke, or congestive heart failure;
- angina (chest pain), high or low blood pressure;
- liver disease;
- kidney disease (or if you are on dialysis);
- a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
- a bleeding disorder such as hemophilia;
- a stomach ulcer;
- retinitis pigmentosa (an inherited condition of the eye);
- a physical deformity of the penis (such as Peyronie's disease); or
- if you have been told you should not have sexual intercourse for health reasons.
Tadalafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking tadalafil, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old.
It is not clear whether tadalafil is the actual cause of vision loss. Stop using tadalafil and get emergency medical help if you have sudden vision loss.
FDA pregnancy category B. Tadalafil is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment with Adcirca.
It is not known whether tadalafil passes into breast milk or if it could harm a nursing baby. Do not use Adcirca without telling your doctor if you are breast-feeding a baby.
How should I take tadalafil (Adcirca)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Tadalafil can be taken with or without food.
Do not break or split a Cialis tablet. Swallow it whole.
Cialis is usually taken only once per day. Follow your doctor's instructions. For erectile dysfunction, take the medicine just before sexual activity but not more than once per day.
Cialis can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. Follow your doctor's instructions.
Adcirca is usually taken once per day. Follow your doctor's instructions. Do not take Cialis for erectile dysfunction if you are taking Adcirca for pulmonary arterial hypertension.
Do not take tadalafil more than once a day. Allow 24 hours to pass between doses. If you take the medication daily, take it at the same time each day.
Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.
Store at room temperature away from moisture and heat.
Additional Adcirca Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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