Adderall (Amphetamine, Dextroamphetamine Mixed Salts) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 8, 2012

Adderall

Narcolepsy »

What is narcolepsy?

Narcolepsy is a chronic disease of the central nervous system. Excessive daytime sleepiness (EDS) is the main symptom and is present in 100% of patients with narcolepsy. Other primary symptoms of narcolepsy include:

loss of muscle tone (cataplexy),
distorted perceptions (hypnagogic hallucinations), and
inability to move or talk (sleep paralysis).

Additional symptoms include disturbed nocturnal sleep and automatic behavior (patients carry out certain actions without conscious awareness). All of the symptoms of narcolepsy may be present in various combinations and degrees of severity.

Narcolepsy usually begins in teenagers or young adults and affects both sexes equally. The first symptom to appear is excessive daytime sleepiness, which may remain unrecognized for a long time in that it develops gradually over time. The other symptoms can follow excessive daytime sleepiness by months...

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ADDERALL® (amphetamine, dextroamphetamine mixed salts)
(amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate)

AMPHETAMINES HAVE A HIGH POTENTIAL FOR ABUSE. ADMINISTRATION OF AMPHETAMINES FOR PROLONGED PERIODS OF TIME MAY LEAD TO DRUG DEPENDENCE AND MUST BE AVOIDED. PARTICULAR ATTENTION SHOULD BE PAID TO THE POSSIBILITY OF SUBJECTS OBTAINING AMPHETAMINES FOR NON-THERAPEUTIC USE OR DISTRIBUTION TO OTHERS, AND THE DRUGS SHOULD BE PRESCRIBED OR DISPENSED SPARINGLY.

MISUSE OF AMPHETAMINE MAY CAUSE SUDDEN DEATH AND SERIOUS CARDIOVASCULAR ADVERSE EVENTS.

DRUG DESCRIPTION

A single-entity amphetamine product combining the neutral sulfate salts of dextroamphetamine and amphetamine, with the dextro isomer of amphetamine saccharate and d, l-amphetamine aspartate monohydrate.

EACH TABLET CONTAINS:	5 mg	7.5 mg	10 mg	12.5 mg	15 mg	20 mg	30 mg
Dextroamphetamine Saccharate	1.25 mg	1.875 mg	2.5 mg	3.125 mg	3.75 mg	5 mg	7.5 mg
Amphetamine Aspartate Monohydrate	1.25 mg	1.875 mg	2.5 mg	3.125 mg	3.75 mg	5 mg	7.5 mg
Dextroamphetamine Sulfate USP	1.25 mg	1.875 mg	2.5 mg	3.125 mg	3.75 mg	5 mg	7.5 mg
Amphetamine Sulfate USP	1.25 mg	1.875 mg	2.5 mg	3.125 mg	3.75 mg	5 mg	7.5 mg
Total amphetamine base equivalence	3.13 mg	4.7 mg	6.3 mg	7.8 mg	9.4 mg	12.6 mg	18.8 mg

Inactive Ingredients:

LACTITOL, MICROCRYSTALLINE CELLULOSE, COLLOIDAL SILICON DIOXIDE, MAGNESIUM STEARATE, AND OTHER INGREDIENTS.

Colors:

ADDERALL® (amphetamine, dextroamphetamine mixed salts) 5 MG IS A WHITE TO OFF-WHITE TABLET, WHICH CONTAINS NO COLOR ADDITIVES.
ADDERALL® (amphetamine, dextroamphetamine mixed salts) 7.5 MG AND 10 MG CONTAIN FD & C BLUE #1.
ADDERALL® (amphetamine, dextroamphetamine mixed salts) 12.5 MG, 15 MG, 20 MG AND 30 MG CONTAIN FD & C YELLOW #6 AS A COLOR ADDITIVE.

What are the possible side effects of amphetamine and dextroamphetamine (Adderall, Adderall XR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using amphetamine and dextroamphetamine and call your doctor at once if you have any of these serious side effects:

fast, pounding, or uneven heartbeats;
feeling light-headed, fainting;
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);...

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What are the precautions when taking amphetamine, dextroamphetamine mixed salts (Adderall)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to sympathomimetic drugs (e.g., epinephrine, pseudoephedrine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain mental/mood conditions (e.g., agitation, psychosis), heart/blood vessel disease (e.g., irregular heartbeat, coronary artery disease, angina, heart failure, cardiomyopathy), problems with heart structure (e.g., valve problems), history of heart attack or stroke, moderate or severe high blood...

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Last reviewed on RxList: 10/4/2010
This monograph has been modified to include the generic and brand name in many instances.