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Adenoscan

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Adenoscan

Overdosage
Contraindications

OVERDOSE

The half-life of adenosine is less than 10 seconds and side effects of Adenoscan (when they occur) usually resolve quickly when the infusion is discontinued, although delayed or persistent effects have been observed. Methylxanthines, such as caffeine and theophylline, are competitive adenosine receptor antagonists and theophylline has been used to effectively terminate persistent side effects. In controlled U.S. clinical trials, theophylline (50-125 mg slow intravenous injection) was needed to abort Adenoscan side effects in less than 2% of patients.

CONTRAINDICATIONS

Intravenous Adenoscan (adenosine injection) should not be administered to individuals with:

  1. Second- or third-degree AV block (except in patients with a functioning artificial pacemaker).
  2. Sinus node disease, such as sick sinus syndrome or symptomatic bradycardia (except in patients with a functioning artificial pacemaker).
  3. Known or suspected bronchoconstrictive or bronchospastic lung disease (e.g., asthma).
  4. Known hypersensitivity to adenosine.

Last reviewed on RxList: 1/21/2014
This monograph has been modified to include the generic and brand name in many instances.

Overdosage
Contraindications
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Additional Adenoscan Information

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