"People who are obese may be more susceptible to environmental food cues than their lean counterparts due to differences in brain chemistry that make eating more habitual and less rewarding, according to a National Institutes of Health study pu"...
The following adverse reactions are described, or described in greater detail, in other sections:
- Primary pulmonary hypertension [see WARNINGS AND PRECAUTIONS]
- Valvular heart disease [see WARNINGS AND PRECAUTIONS]
- Effect on the ability to engage in potentially hazardous tasks [see WARNINGS AND PRECAUTIONS]
- Withdrawal effects following prolonged high dosage administration [see Drug Abuse and Dependence]
The following adverse reactions to phentermine have been identified:
Central Nervous System
Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances.
Read the Adipex-P (phentermine hydrochloride) Side Effects Center for a complete guide to possible side effects
Monoamine Oxidase Inhibitors
Use of ADIPEX-P® is contraindicated during or within 14 days following the administration of monoamine oxidase inhibitors because of the risk of hypertensive crisis.
Concomitant use of alcohol with ADIPEX-P® may result in an adverse drug reaction.
Insulin And Oral Hypoglycemic Medications
Requirements may be altered [see WARNINGS AND PRECAUTIONS].
Adrenergic Neuron Blocking Drugs
Drug Abuse And Dependence
Phentermine is a Schedule IV controlled substance.
Phentermine is related chemically and pharmacologically to the amphetamines. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of phentermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program.
Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage of these drugs to many times than recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. A severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia.
Read the Adipex-P Drug Interactions Center for a complete guide to possible interactions
Last reviewed on RxList: 5/16/2016
Additional Adipex-P Information
Adipex-P - User Reviews
Adipex-P User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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