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A sterile solution intended for subcutaneous or intramuscular injection. When diluted, it may also be administered intracardially or intravenously. It may also be administered intraspinally by adding to anesthetic spinal fluid mixture. Each milliliter contains 1 mg Adrenalin (epinephrine) as the hydrochloride dissolved in Water for Injection, USP, with sodium chloride added for isotonicity.

1 mL Vial

Contains not more than 0.1% sodium bisulfite as an antioxidant, and the air in the vial has been displaced by nitrogen.

30 mL Vial

Contains 0.5%Chlorobutanol (chloroform derivative) as a preservative and not more than 0.15% sodium bisulfite as an antioxidant.

Epinephrine is the active principle of the adrenal medulla, chemically described as (—)-3,4-Dihydroxy-α-[(methylamino) methyl] benzyl alcohol, and has the following structural formula:

Last reviewed on RxList: 3/30/2009
This monograph has been modified to include the generic and brand name in many instances.