"By Kathleen Doheny
WebMD Health News
Reviewed by Arefa Cassoobhoy, MD, MPH
March 10, 2015 -- Drugs known as biologics have grabbed headlines over the years, both for their potential in fighting cancer and other diseases, and f"...
Afinitor Patient Information including If I Miss a Dose
In this Article
- What is everolimus (Afinitor) (Afinitor)?
- What are the possible side effects of Afinitor (Afinitor)?
- What is the most important information I should know about Afinitor (Afinitor)?
- What should I discuss with my health care provider before taking Afinitor (Afinitor)?
- How should I take Afinitor (Afinitor)?
- What happens if I miss a dose (Afinitor)?
- What happens if I overdose (Afinitor)?
- What should I avoid while taking Afinitor (Afinitor)?
- What other drugs will affect Afinitor (Afinitor)?
- Where can I get more information?
What happens if I miss a dose (Afinitor)?
If you are less than 6 hours late in taking your medicine, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Afinitor)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Afinitor (Afinitor)?
Do not receive a "live" vaccine while taking everolimus, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), oral polio, typhoid, chickenpox (varicella), BCG (Bacillus Calmette and Guérin), and nasal flu vaccine.
Grapefruit and grapefruit juice may interact with everolimus and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.
What other drugs will affect Afinitor (Afinitor)?
Many drugs can interact with everolimus. Below is just a partial list. Tell your doctor if you are using:
- aprepitant (Emend);
- bosentan (Tracleer);
- conivaptan (Vaprisol);
- dexamethasone (Cortastat, Dexasone, Solurex, DexPak);
- imatinib (Gleevec);
- isoniazid (for treating tuberculosis);
- St. John's wort;
- an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), rifapentine (Priftin), or telithromycin (Ketek);
- an antidepressant such as nefazodone;
- antifungal medication such as clotrimazole (Mycelex Troche), itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig), or voriconazole (Vfend);
- a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton);
- heart or blood pressure medication such as amiodarone (Cordarone, Pacerone), diltiazem (Cartia, Cardizem), dronedarone (Multaq), nicardipine (Cardene), quinidine (Quin-G), or verapamil (Calan, Covera, Isoptin, Verelan);
- HIV or AIDS medication such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Atripla, Sustiva), etravirine (Intelence), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), saquinavir (Invirase), or ritonavir (Kaletra, Norvir);
- medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf).
- medicines to treat narcolepsy, such as armodafinil (Nuvigil) or modafinil (Progivil); or
- seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenobarbital (Solfoton), phenytoin (Dilantin), or primidone (Mysoline).
This list is not complete and there are many other drugs that can interact with everolimus. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about everolimus (Afinitor).
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2013 Cerner Multum, Inc. Version: 10.01. Revision date: 8/13/2012.
Your use of the content provided in this service indicates that you have read,understood and agree to the End-User License Agreement,which can be accessed by clicking on this link.
Additional Afinitor Information
- Afinitor Drug Interactions Center: everolimus oral
- Afinitor Side Effects Center
- Afinitor Overview including Precautions
- Afinitor FDA Approved Prescribing Information including Dosage
Afinitor - User Reviews
Afinitor User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get the latest treatment options.