July 28, 2016
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Afrezza

"In the first study to examine whether the calcium-channel blocker verapamil lowers glucose in humans (as it does in mice), this old drug that has long been used to treat hypertension, cardiac arrhythmia, and migraine was indeed associated with a "...

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Afrezza

Overdosage
Contraindications

OVERDOSE

Excess insulin administration may cause hypoglycemia and hypokalemia [see WARNING AND PRECAUTIONS].

Mild episodes of hypoglycemia can usually be treated with oral glucose. Adjustments in drug dosage, meal patterns, or exercise, may be needed.

Severe episodes of hypoglycemia with coma, seizure, or neurologic impairment may be treated with intramuscular / subcutaneous glucagon or concentrated intravenous glucose. After apparent clinical recovery from hypoglycemia, continued observation and additional carbohydrate intake may be necessary to avoid recurrence of hypoglycemia. Hypokalemia must be corrected appropriately.

CONTRAINDICATIONS

AFREZZA is contraindicated in patients with the following:

  • During episodes of hypoglycemia
  • Chronic lung disease, such as asthma or chronic obstructive pulmonary disease (COPD), because of the risk of acute bronchospasm [see WARNING AND PRECAUTIONS].
  • Hypersensitivity to regular human insulin or any of the AFREZZA excipients [see WARNING AND PRECAUTIONS].
This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 3/3/2016

Overdosage
Contraindications

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