July 29, 2016
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Aggrastat

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Aggrastat




Overdosage
Contraindications

OVERDOSE

In clinical trials, inadvertent overdosage with AGGRASTAT occurred in doses up to 2 times the recommended dose for initial infusion doses. Inadvertent overdosage occurred in doses up to 9.8 times the 0.15 mcg/kg/min maintenance infusion rate.

The most frequently reported manifestation of overdosage was bleeding, primarily minor mucocutaneous bleeding events and minor bleeding at the sites of cardiac catheterization [see WARNINGS AND PRECAUTIONS].

Overdosage of AGGRASTAT should be treated by assessment of the patient’s clinical condition and cessation or adjustment of the drug infusion as appropriate.

AGGRASTAT can be removed by hemodialysis.

CONTRAINDICATIONS

AGGRASTAT is contraindicated in patients with:

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 7/6/2016

Overdosage
Contraindications

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