DRUG INTERACTIONS: The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.

Some products that may interact with this drug include: certain antidepressants that affect serotonin (such as amitriptyline, SSRIs and SNRIs including paroxetine/venlafaxine), aspirin/NSAIDs (such as ibuprofen, ketorolac, naproxen), "blood thinners" (such as warfarin, heparin, other anti-platelet drugs), corticosteroids (such as prednisone), live viral vaccine (such as influenza given in nose, varicella-chicken pox/shingles), mifepristone, ginkgo biloba.

Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (aspirin, NSAIDs such as ibuprofen, naproxen) that are similar to this drug and may increase your risk of side effects if taken together. Ask your pharmacist about using those products safely.

However, if your doctor has directed you to take low-dose aspirin for heart attack prevention (usually at dosages of 81-325 milligrams a day), ask your doctor if you should continue taking the aspirin. The low dose of aspirin in this product may not be enough to protect against heart attack.

This medication may interfere with certain laboratory/medical tests possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.

OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: ringing in the ears, flushing, sweating, restlessness, weakness, dizziness, fast heartbeat.

NOTES: Do not share this medication with others.

Laboratory and/or medical tests (such as bleeding times, blood counts, kidney and liver function tests) may be performed periodically to monitor your progress or check for side effects. Keep all medical and laboratory appointments.

MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-800-854-1166 (US) or 1-800-668-1507 (Canada).

Information last revised July 2010. Copyright(c) 2010 First Databank, Inc.