"In a traditional corneal transplant, the central part of the cornea is removed and a donor cornea is sutured in its place. Image courtesy of Dr. Edward Holland, University of Cincinnati.
Ten years after a transplant, a cornea fro"...
DOSAGE AND ADMINISTRATION
Inject the contents of the ampule or vial rapidly into the antecubital vein, after taking precautions to avoid extravasation. A scalp (butterfly) needle attached to a small syringe is ideal for administration. A syringe, filled with fluorescein, is attached to transparent tubing and a 25 gauge scalp vein needle for injection.
Insert the needle and draw the patient's blood to the hub of the syringe so that a small air bubble separates the patient's blood in the tubing from the fluorescein. With the room lights on, slowly inject the blood back into the vein while watching the skin over the needle tip. If the needle has extravasated, the patient's blood will be seen to bulge the skin and the injection should be stopped before any fluorescein is injected. When assured that extravasation has not occurred, the room light may be turned off and the fluorescein injection completed. Luminescence appears in the retina and choroidal vessels in 9 to 14 seconds and can be observed by standard viewing equipment. If potential allergy is suspected, an intradermal skin test may be performed prior to intravenous administration, i.e., 0.05 mL injection intradermally to be evaluated 30 to 60 minutes following injection. For pediatric patients, the dose is calculated on the basis of 35 mg for each ten pounds of body weight. Parenteral drug products should be inspected visually for particulate matter and discoloration, whenever solution and container permit.
AK-FLUOR®, 10% (Fluorescein Injection, USP - Sterile) 100 mg/mL
NDC 17478-253-10 5 mL single dose vials in packs of
NDC 17478-254-10 5 mL ampules in packs of 25
AK-FLUOR®, 25% (Fluorescein Injection, USP - Sterile) 250 mg/Ml
NDC 17478-250-20 2 mL single dose vials in packs of
NDC 17478-251-20 2 mL ampules in packs of 12
Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature]; protect from freezing.
FL00N Rev. 08/05. Akorn Inc., Buffalo Grove, IL 60089. For product inquiry: 1 800 93AKORN (1-800-932-5676) www.akorn.com. FDA revision date: 8/8/2008
Last reviewed on RxList: 9/23/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Ak-Fluor Information
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