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Akineton Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Akineton (biperiden hydrochloride) Tablet is used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. It is also used to treat and prevent these same muscular conditions when they are caused by drugs such as chlorpromazine, fluphenazine, perphenazine, and others. It is an anticholinergic antiparkinson agent. Common side effects include dry mouth, blurred vision, drowsiness, euphoria or disorientation, urinary retention, dizziness when standing up, constipation, agitation, disturbed behavior.
The usual starting dose of Akineton to treat Parkinson's disease is one tablet taken orally three or four times daily. The dosage is individualized and may be increased to a maximum of 8 tablets (16 mg) per 24 hours. To treat drug-induced extrapyramidal symptoms, the dose is one tablet one to three times daily. Akineton may interact with narcotic pain relievers, phenothiazines and other antipsychotic medications, tricyclic antidepressants, antiarrhythmics, or antihistamines. Tell your doctor all medications you are taking. Akineton should be given during pregnancy only if prescribed. It is not known whether this drug is passed in breast milk. Consult your doctor before breast-feeding.
Our Akineton (biperiden hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Akineton in Detail - Patient Information: Side Effects
If you experience any of the following serious side effects, stop taking biperiden and seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- unusual fever;
- fast or irregular heartbeat;
- anxiety, hallucinations, confusion, agitation, hyperactivity, or loss of consciousness;
- a rash; or
- eye pain.
Other, less serious side effects may be more likely to occur. Continue to take biperiden and talk to your doctor if you experience
- a dry mouth;
- large pupils or blurred vision;
- difficulty urinating or constipation;
- nervousness or anxiety;
- upset stomach; or
- decreased sweating.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Akineton (Biperiden) »
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Akineton FDA Prescribing Information: Side Effects
Atropine-like side effects such as dry mouth; blurred vision; drowsiness; euphoria or disorientation; urinary retention; postural hypotension; constipation; agitation; disturbed behavior may been seen. A case of generalized choreic movements has been reported in a Parkinson's disease patient when biperiden was added to carbidopa/levodopa. A reduction in rapid eye movement (REM) sleep, characterized by increased REM latency and decreased percentage of REM sleep, has been reported. There usually are no significant changes in blood pressure or heart rate in patients who have been given the parenteral form of AKINETON (biperiden) . Mild transient postural hypotension and bradycardia may occur. These side effects can be minimized or avoided by slow intravenous administration. No local tissue reactions have been reported following intramuscular injection. If gastric irritation occurs following oral administration, it can be avoided by administering the drug during or after meals.
The central anticholinergic syndrome can occur as an adverse reaction to properly prescribed anticholinergic medication. See OVERDOSAGE section for signs and symptoms of the central anticholinergic syndrome, and for treatment.
Read the entire FDA prescribing information for Akineton (Biperiden) »
Additional Akineton Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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