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Aldactone

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The amount of fluid (water) retained by the body is controlled primarily by the kidneys. This occurs due to the kidney's ability to control the retention and elimination of sodium and chlorid"...

Aldactone

Aldactone®
(spironolactone) Tablets, USP

Aldactone

ALDACTONE has been shown to be a tumorigen in chronic toxicity studies in rats (see PRECAUTIONS). ALDACTONE should be used only in those conditions described under Indications and Usage. Unnecessary use of this drug should be avoided.

DRUG DESCRIPTION

ALDACTONE oral tablets contain 25 mg, 50 mg, or 100 mg of the aldosterone antagonist spironolactone, 17-hydroxy-7α-mercapto-3-oxo-17α-pregn-4-ene-21carboxylic acid γ-lactone acetate, which has the following structural formula:

Aldactone® spironolactone Structural Formula Illustration

Spironolactone is practically insoluble in water, soluble in alcohol, and freely soluble in benzene and in chloroform.

Inactive ingredients include calcium sulfate, corn starch, flavor, hypromellose, iron oxide, magnesium stearate, polyethylene glycol, povidone, and titanium dioxide.

What are the possible side effects of spironolactone (Aldactone)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using spironolactone and call your doctor at once if you have a serious side effect such as:

  • numbness or tingly feeling;
  • muscle pain or weakness;
  • slow, fast, or uneven heart rate;
  • feeling drowsy, restless, or light-headed;
  • urinating less than usual or not at all;
  • shallow breathing;
  • tremors, confusion;
  • nausea, upper stomach pain, itching, loss of...

Read All Potential Side Effects and See Pictures of Aldactone »

What are the precautions when taking spironolactone (Aldactone)?

Before taking spironolactone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: no urine output (anuria), severe kidney disease, high blood potassium (hyperkalemia).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver or kidney problems, untreated mineral imbalance (e.g., low sodium).

Before having surgery, tell your doctor or dentist that you are taking this medication.

This...

Read All Potential Precautions of Aldactone »

Last reviewed on RxList: 10/1/2012
This monograph has been modified to include the generic and brand name in many instances.

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Aldactone - User Reviews

Aldactone User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Aldactone sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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