"Nov. 1, 2012 -- Having even mildly elevated blood pressure at midlife prematurely ages the brain, a new study shows.
Researchers say the early changes seen with higher blood pressure may set the stage for problems with thinking, memor"...
(spironolactone) Tablets, USP
ALDACTONE has been shown to be a tumorigen in chronic toxicity studies in rats (see PRECAUTIONS). ALDACTONE should be used only in those conditions described under Indications and Usage. Unnecessary use of this drug should be avoided.
ALDACTONE oral tablets contain 25 mg, 50 mg, or 100 mg of the aldosterone antagonist spironolactone, 17-hydroxy-7α-mercapto-3-oxo-17α-pregn-4-ene-21carboxylic acid γ-lactone acetate, which has the following structural formula:
Inactive ingredients include calcium sulfate, corn starch, flavor, hypromellose, iron oxide, magnesium stearate, polyethylene glycol, povidone, and titanium dioxide.
What are the possible side effects of spironolactone (Aldactone)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using spironolactone and call your doctor at once if you have a serious side effect such as:
- numbness or tingly feeling;
- muscle pain or weakness;
- slow, fast, or uneven heart rate;
- feeling drowsy, restless, or light-headed;
- urinating less than usual or not at all;
- shallow breathing;
- tremors, confusion;
- nausea, upper stomach pain, itching, loss of...
What are the precautions when taking spironolactone (Aldactone)?
Before taking spironolactone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: high blood potassium (hyperkalemia), inability to urinate (anuria), kidney problems, liver problems, untreated mineral imbalance (e.g., low sodium), decreased adrenal gland function (Addison's disease).
Before having surgery, tell your doctor or dentist that you are taking this medication.
This medication may increase your potassium levels. Before using potassium supplements or salt substitutes that contain...
Last reviewed on RxList: 10/1/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Aldactone Information
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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