Brand Names: Aldoril 15, Aldoril 25, Aldoril D30, Aldoril D50

Generic Name: hydrochlorothiazide and methyldopa (Pronunciation: HYE droe KLOR oh THYE a zide and METH il DOE pa)

• What is methyldopa and hydrochlorothiazide (Aldoril)?
• What are the possible side effects of methyldopa and hydrochlorothiazide (Aldoril)?
• What is the most important information I should know about methyldopa and hydrochlorothiazide (Aldoril)?
• What should I discuss with my doctor before taking methyldopa and hydrochlorothiazide (Aldoril)?
• How should I take methyldopa and hydrochlorothiazide (Aldoril)?
• What happens if I miss a dose (Aldoril)?
• What happens if I overdose (Aldoril)?
• What should I avoid while taking methyldopa and hydrochlorothiazide (Aldoril)?
• What other drugs will affect methyldopa and hydrochlorothiazide (Aldoril)?
• Where can I get more information?

What is methyldopa and hydrochlorothiazide (Aldoril)?

Methyldopa and hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Methyldopa and hydrochlorothiazide is used to treat high blood pressure (hypertension).

Methyldopa and hydrochlorothiazide may also be used for other purposes not listed in this medication guide.

HCT-Methyldopa 15 mg-250 mg-MYL

round, green, imprinted with 507, MYLAN

HCTZ-Methyldopa 250 mg-25 mg-MYL

oblong, green, imprinted with 711, MYLAN

What are the possible side effects of methyldopa and hydrochlorothiazide (Aldoril)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:

• dry mouth, thirst, nausea, vomiting;
• feeling drowsy, restless, or light-headed;
• chest pain, fast or uneven heartbeat;
• muscle pain or weakness;
• jerky or rolling muscle movements that you cannot control;
• confusion, unusual thoughts or behavior;
• skin rash, bruising, severe tingling, numbness;
• painful or difficult urination;
• urinating less than usual or not at all;
• swelling in your face, stomach, hands, or feet;
• a red, blistering, peeling skin rash;
• pale or yellowed skin, dark colored urine, fever, confusion or weakness; or
• joint pain or swelling with fever, chest pain, or tired feeling.

Less serious side effects may include:

• mild nausea, vomiting, loss of appetite, diarrhea or constipation;
• soreness or black discoloration of your tongue;
• headache;
• dizziness, spinning sensation;
• muscle or joint pain; or
• blurred vision.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about methyldopa and hydrochlorothiazide (Aldoril)?

You should not use this medication if you are allergic to methyldopa (Apresoline) or hydrochlorothiazide, if you are unable to urinate, or if you have liver disease (including cirrhosis or hepatitis), or a history of liver problems caused by taking methyldopa.

Do not take this medication if you are have taken an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.

Before using methyldopa and hydrochlorothiazide, tell your doctor if you have kidney disease (or are on dialysis), angina pectoris (chest pain), asthma or allergies, gout, lupus, diabetes, an allergy to sulfa drugs, or if you have ever had a stroke.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

There are many other medicines that can interact with methyldopa and hydrochlorothiazide. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.