"NEW YORK (Reuters Health) - Inflammation and immunodeficiency related to chronic sinusitis are not significant risks for head and neck cancers, and "at most" play a "modest role" in certain rare types, researchers from the US National Cancer Inst"...
Patients should be informed that the major acute toxicities of melphalan are related to bone marrow suppression, hypersensitivity reactions, gastrointestinal toxicity, and pulmonary toxicity. The major long-term toxicities are related to infertility and secondary malignancies. Patients should never be allowed to take the drug without close medical supervision and should be advised to consult their physicians if they experience skin rash, signs or symptoms of vasculitis, bleeding, fever, persistent cough, nausea, vomiting, amenorrhea, weight loss, or unusual lumps/masses. Women of childbearing potential should be advised to avoid becoming pregnant.
Last reviewed on RxList: 11/16/2016
This monograph has been modified to include the generic and brand name in many instances.
Additional Alkeran Injection Information
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