"Cancer patients with limited finances are more likely to have increased symptoms and poorer quality of life, say the authors of a new study published online February 29 in the Journal of Clinical Oncology.
Patients should be informed that the major acute toxicities of melphalan are related to bone marrow suppression, hypersensitivity reactions, gastrointestinal toxicity, and pulmonary toxicity. The major long-term toxicities are related to infertility and secondary malignancies. Patients should never be allowed to take the drug without close medical supervision and should be advised to consult their physicians if they experience skin rash, signs or symptoms of vasculitis, bleeding, fever, persistent cough, nausea, vomiting, amenorrhea, weight loss, or unusual lumps/masses. Women of childbearing potential should be advised to avoid becoming pregnant.
Last reviewed on RxList: 11/16/2016
This monograph has been modified to include the generic and brand name in many instances.
Additional Alkeran Injection Information
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