"May 26, 2010 -- The popular weight loss products Alli and Xenical have been linked to a rare but severe form of liver injury, the FDA today warned.
The risk appears tiny. Worldwide, there have been only 13 cases among the 40 million peo"...
(orlistat 60 mg) Capsules
The active ingredient in alli (orlistat 60 mg) (orlistat) has been used in the United States as a prescription-only medication at double the dose found in alli (orlistat 60 mg) . Xenical® (orlistat 120 mg/TID) was introduced in the United States in 1999 following rigorous clinical studies and FDA approval. Orlistat has an extensive clinical history. It has had 25 million patient treatments and has been studied in more than 100 controlled clinical trials.
Behavior Support programs are part of the foundation for successful weight loss. Xenical® provided a separate support program for patients known as Xenicare, which, at the time, was considered a comprehensive plan. But a lot has changed since the introduction of Xenical®, including consumer expectations, healthcare professional involvement within the weight loss category and consumer, information utilization, namely, the sophistication of the Internet user. Applying learnings from Xenicare, our insights from consumers & healthcare professionals, and our understanding of current Internet usage, we have developed the alli (orlistat 60 mg) support program, called myalli (orlistat 60 mg) plan. The myalli (orlistat 60 mg) plan is an individually tailored support plan based on sound clinical practices and designed by nutrition and weight loss experts. It is free with the purchase of alli (orlistat 60 mg) . The myalli (orlistat 60 mg) plan.com is an extremely comprehensive online support program, including personalized online pages to view goals, check-ins with individualized feedback and advice, continuous follow-up and weekly monitoring, personalized emails on eating right/meal planning, guidance on treatment effects, online journal, menus and shopping lists, direct advice from clinical experts and a connection to a community of other alli (orlistat 60 mg) users. Research indicates that those who receive one-on-one counseling or online support may have a long-term advantage in successfully losing weight.
alli (orlistat 60 mg) is different than Xenical® because it offers informational materials with the actual product. The alli (orlistat 60 mg) starter pack includes over 200 pages of free in-pack materials to help guide individuals through the alli (orlistat 60 mg) program and set expectations for gradual weight loss, help them make healthy eating choices, monitor daily diets, and manage treatment effects. Eighty percent of patients found these materials to be very helpful. Overall, the alli (orlistat 60 mg) program offers unprecedented support and resources designed to help modify behavior by creating self-assessment and self-management skills. Assuming personal responsibility is integral to achieving sustainable weight loss.
Another difference when comparing alli (orlistat 60 mg) to Xenical® is the manageability and tolerability of GI events. In clinical studies, the 60-mg capsule of alli (orlistat 60 mg) demonstrated comparable efficacy and safety profiles to the 120-mg prescription capsule, but had a lower incidence of treatment effects, compared with the 120-mg dosage. Only a small percentage of trial subjects withdrew due to GI-AEs (5.4% on 120mg compared to only 3.2% on 60-mg), further reinforcing the tolerability of the 60mg dose. After 90 days of using alli (orlistat 60 mg) , 81% of study participants reported being satisfied or very satisfied with orlistat, and 91% reported losing weight. In addition, alli (orlistat 60 mg) will tell consumers and HCPs alike that the likelihood of treatment effects is greater if individuals aren't committed to following a reduced-calorie, low-fat diet (no more than 15 grams of fat per meal) and eating smaller portions.
alli (orlistat 60 mg) is available for oral administration in dark-blue, hard-gelatin capsules. Each capsule contains 60 mg of the active ingredient, orlistat. The capsules also contain the inactive ingredients FD&C Blue No. 2, edible ink, gelatin, iron dioxide, microcrystalli (orlistat 60 mg) ne cellulose, povidone, sodium lauryl sulfate, sodium starch glycolate, talc, titanium dioxide.
What are the possible side effects of orlistat (alli, Xenical)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using orlistat and call your doctor at once if you have a serious side effect such as:
- severe pain in your lower back, blood in your urine;
- urinating less than usual or not at all;
- drowsiness, confusion, mood changes, increased thirst;
- swelling, weight gain, feeling short of breath;
- severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart...
What are the precautions when taking orlistat 60 mg (Alli)?
Before taking orlistat, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain digestive problem (chronic malabsorption syndrome), a certain gall bladder problem (cholestasis), underactive thyroid (hypothyroidism), kidney stones/problems (such as calcium oxalate kidney stones, hyperoxaluria), certain eating disorders (anorexia nervosa/bulimia), seizures.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs,...
Last reviewed on RxList: 6/20/2007
This monograph has been modified to include the generic and brand name in many instances.
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