"A class of medications long used to curb HIV infection shows promise as a therapy for age-related macular degeneration (AMD), suggest findings from an NIH-funded study. These mainstay HIV drugs, called nucleoside reverse transcriptase inhibitors "...
(lodoxamide tromethamine) Ophthalmic Solution 0.1%
ALOMIDE® (lodoxamide tromethamine ophthalmic solution) 0.1% is a sterile ophthalmic solution containing the mast cell stabilizer lodoxamide tromethamine for topical administration to the eyes. Lodoxamide tromethamine is a white, crystalline, water-soluble powder with a molecular weight of 553.91. The chemical structure is presented below:
N,N'-(2-chloro-5-cyano-m-phenylene)dioxamic acid tromethamine salt
Molecular Formula: C19H28O12N5Cl
Each mL of ALOMIDE® (lodoxamide tromethamine ophthalmic solution) 0.1% contains: Active: 1.78 mg lodoxamide tromethamine equivalent to 1 mg lodoxamide. Preservative: benzalkonium chloride 0.007%. Inactive: mannitol, hypromellose 2910, sodium citrate, citric acid, edetate disodium, tyloxapol, hydrochloric acid and/or sodium hydroxide (adjust pH), and purified water.
What are the possible side effects of lodoxamide ophthalmic (Alomide)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using lodoxamide and call your doctor at once if you have severe burning or stinging when you apply the eye drops, or for long periods of time after using the drops.
Less serious side effects may include:
- mild burning, stinging, or eye irritation;
- eye itching, watering, pain, or redness;
- blurred vision;
- dry eyes;
- swollen or puffy eye lids;
What are the precautions when taking lodoxamide tromethamine (Alomide)?
Before using lodoxamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history.
After you apply this drug, your vision may become temporarily blurred. Also, this drug may rarely make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.
During pregnancy, this medication should be used only when clearly needed. Discuss...
Last reviewed on RxList: 8/14/2008
This monograph has been modified to include the generic and brand name in many instances.
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