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In this Article

• What is palonosetron (Aloxi Capsules)?
• What are the possible side effects of palonosetron (Aloxi Capsules)?
• What is the most important information I should know about palonosetron (Aloxi Capsules)?
• What should I discuss with my health care provider before receiving palonosetron (Aloxi Capsules)?
• How is palonosetron given (Aloxi Capsules)?
• What happens if I miss a dose (Aloxi Capsules)?
• What happens if I overdose (Aloxi Capsules)?
• What should I avoid after receiving palonosetron (Aloxi Capsules)?
• What other drugs will affect palonosetron (Aloxi Capsules)?
• Where can I get more information?

What should I discuss with my health care provider before receiving palonosetron (Aloxi Capsules)?

You should not receive this medication if you are allergic to palonosetron.

Before you receive palonosetron, tell your doctor if you have:

• an electrolyte imbalance such as low levels of potassium or magnesium in your blood;
• a personal or family history of "Long QT syndrome";
• if you are taking a diuretic (water pill);
• if you are taking a heart rhythm medication; or
• if you have ever had an allergic reaction to dolasetron (Anzemet), granisetron (Kytril), or ondansetron (Zofran).

If you have any of these conditions, you may not be able to use palonosetron, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether palonosetron passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is palonosetron given (Aloxi Capsules)?

Palonosetron is given as an injection through a needle placed into a vein. You will receive this injection in a hospital or cancer treatment setting.

Palonosetron is usually given within 30 minutes before the start of your chemotherapy treatment.