April 27, 2017


(retapamulin) Ointment


ALTABAX contains retapamulin, a semisynthetic pleuromutilin antibiotic. The chemical name of retapamulin is acetic acid, [[(3-exo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9- propano-3aH-cyclopentacycloocten-8-yl ester. Retapamulin, a white to pale-yellow crystalline solid, has a molecular formula of C30H47NO4S, and a molecular weight of 517.78. The chemical structure is:

ALTABAX (retapamulin) Structural Formula Illustration

Each gram of ointment for dermatological use contains 10 mg of retapamulin in white petrolatum.

What are the possible side effects of retapamulin topical (Altabax)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using retapamulin and call your doctor at once if you have severe burning, itching, redness, swelling, blistering, oozing, or other skin irritation where the medicine was applied.

Less serious side effects may include:

  • mild skin irritation;
  • nausea, diarrhea;
  • headache; or
  • stuffy nose, sore throat.

This is not a complete list of side effects and others may...

Read All Potential Side Effects and See Pictures of Altabax »

What are the precautions when taking retapamulin (Altabax)?

Before using retapamulin, tell the doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell the doctor or pharmacist your medical history.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before...

Read All Potential Precautions of Altabax »

Last reviewed on RxList: 12/5/2016
This monograph has been modified to include the generic and brand name in many instances.

Altabax - User Reviews

Altabax User Reviews

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Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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