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Altoprev

What are statins and how do they work?

Statins (or HMG-CoA reductase inhibitors) are a class of drugs that reduce cholesterol in individuals who have dyslipidemia (abnormal fats in the blood) and thus are at risk for cardiovascular disease. Dyslipidemia may involve an elevation of total cholesterol, a reduction of low density lipoprotein (LDL) cholesterol and/or triglycerides, or a reduction of high density lipoprotein (HDL) cholesterol in blood. Statins work by blocking the enzyme in the liver that is responsible for making cholesterol. This enzyme is called hydroxy-methylglutaryl-coenzyme A reductase (HMG-CoA reductase).

Cholesterol is described as a soft wax-like fatty substance that is found in the blood stream and in cells. It is important to note that cholesterol is a naturally existing substance in all individuals from birth and its presence is actually necessary for promoting an overall healthy body. About 75% of cholesterol is produced by the liver and oth...

Altoprev

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PATIENT INFORMATION

The ALTOPREV® (lovastatin extended-release tablets) extended-release tablets should be swallowed whole and not chewed, crushed or cut.

Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness (see WARNINGS, Myopathy/Rhabdomyolysis).

Last reviewed on RxList: 7/31/2007
This monograph has been modified to include the generic and brand name in many instances.

Altoprev - User Reviews

Altoprev User Reviews

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Cholesterol Management

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