"Nov. 5, 2012 (Los Angeles) -- An IV infusion of "good" HDL cholesterol seems to rapidly remove cholesterol out of plaque-clogged arteries following a heart attack, a small, early study suggests.
The goal of the new treatment is to red"...
Patients taking Altoprev® should be advised that cholesterol is a chronic condition and they should adhere to their medication along with their National Cholesterol Education Program (NCEP)- recommended diet, a regular exercise program as appropriate, and periodic testing of a fasting lipid panel to determine goal attainment.
Patients should be advised about substances they should not take concomitantly with lovastatin [see WARNINGS AND PRECAUTIONS]. Patients should also be advised to inform other healthcare professionals prescribing a new medication that they are taking Altoprev.
All patients starting therapy with Altoprev should be advised of the risk of myopathy, including rhabdomyolysis, and told to report promptly any unexplained muscle pain, tenderness, or weakness particularly if accompanied by malaise or fever or if these muscle signs or symptoms persist after discontinuing Altoprev. The risk of this occurring is increased when taking certain types of medication or consuming grapefruit juice. Patients should discuss all medication, both prescription and over the counter, with their healthcare professional.
It is recommended that liver enzyme tests be performed before the initiation of Altoprev and if signs or symptoms of liver injury occur. All patients treated with Altoprev should be advised to report promptly any symptoms that may indicate liver injury, including fatigue, anorexia, right upper abdominal discomfort, dark urine, or jaundice.
Women of childbearing age should be advised to use an effective method of birth control to prevent pregnancy while using Altoprev. Discuss future pregnancy plans with your patients, and discuss when to stop Altoprev if they are trying to conceive. Patients should be advised that if they become pregnant, they should stop taking Altoprev and call their healthcare professional.
Women who are breastfeeding should be advised to not use Altoprev. Patients, who have a lipid disorder and are breastfeeding, should be advised to discuss the options with their healthcare professional.
Last reviewed on RxList: 12/12/2016
This monograph has been modified to include the generic and brand name in many instances.
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