August 4, 2015
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Alzheimer's Disease Causes, Stages, and Symptoms (cont.)

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Ten warning signs of Alzheimer's disease

The Alzheimer's Association has developed the following list of warning signs that include common symptoms of Alzheimer's disease. Individuals who exhibit several of these symptoms should see a physician for a complete evaluation.

  1. Memory loss (forgetting important dates or events)
  2. Difficulty performing familiar tasks (problems remembering the rules to a favorite game or driving to a familiar place)
  3. Problems talking with others or writing (For example, a person may struggle to find the right words for items or names of people or places.)
  4. Disorientation to time and place (for example, forgetting where they are, loosing track of the seasons, dates, and passage of time)
  5. Poor or decreased judgment (for example, poor hygiene or poor judgment when dealing with money or financial matters)
  6. Vision problems (problems reading or judging distances)
  7. Problems with solving problems or planning (for example, problems tracking regular bills or following familiar recipes)
  8. Misplacing things (for example, a person put items in unusual places and then are not able to retrace their steps find them again)
  9. Changes in mood, personality, or behavior
  10. Loss of initiative or withdrawal from social or work activities

It is normal for certain kinds of memory, such as the ability to remember lists of words, to decline with normal aging. In fact, normal individuals 50 years of age will recall only about 60% as many items on some kinds of memory tests as individuals 20 years of age. Furthermore, everyone forgets, and every 20 year old is well aware of multiple times he or she couldn't think of an answer on a test that he or she once knew. Almost no 20 year old worries when he/she forgets something, that he/she has the 'early stages of Alzheimer's disease,' whereas an individual 50 or 60 years of age with a few memory lapses may worry that they have the 'early stages of Alzheimer's disease.'

Mild cognitive impairment

The criteria for dementia are conservative meaning that a patient must have had considerable decline in the ability to think before a diagnosis of dementia is appropriate. The progression of Alzheimer's disease is so insidious and slow that patients go through a period of decline where their memory is clearly worse than its baseline, yet they still do not meet criteria for dementia. This transitional syndrome is called Mild Cognitive Impairment (MCI). Individuals affected with MCI have cognitive impairment that is demonstrated on formal neuropsychological testing but are still able to function well. Formal neuropsychological testing usually means that the patient is administered a battery of standardized tests of memory and thinking. Some of these tests are something like the IQ tests we may have taken in school. When these tests were developed they were administered to hundreds or thousands of people so that statistics are available to say how a person's score compares to a sample of healthy persons of the same age. If a person scores in the top 50%, it means that he or she did better than at least 50% of other normal people who took the test. Persons with lower scores - often in the bottom 7% - are considered to have MCI.

There are several forms of MCI. Perhaps the most common is associated with impairment in memory but not in the ability to plan and reason. Persons with this type called "amnestic MCI" (amnestic comes from "amnesia" and means no memory) have a high risk of developing Alzheimer's disease over the next few years. Persons with preserved memory but impaired reasoning or impaired judgment (call non-amnestic MCI) have a lower risk of developing Alzheimer's disease.

As treatments are developed that decrease the risk of developing Alzheimer's disease or slow its rate of progression (as of June 2007, no such medication has been approved by the FDA), recognition of amnestic MCI will be increasingly important. It is hoped that medications will be developed that will slow the rate of progression of MCI to Alzheimer's disease or completely prevent the development of Alzheimer's disease.

Medically Reviewed by a Doctor on 3/20/2015

Source: MedicineNet.com
http://www.medicinenet.com/alzheimers_disease_causes_stages_and_symptoms/article.htm

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