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Ambisome

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Ambisome

Ambisome

Ambisome Patient Information including If I Miss a Dose

What happens if I miss a dose (Ambisome)?

Since amphotericin B liposomal is usually given while you are in the hospital, it is not likely you will miss a dose of this medication.

If you are receiving amphotericin B liposomal in an outpatient clinic, call your doctor if you will miss an appointment for your amphotericin B liposomal injection.

What happens if I overdose (Ambisome)?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of an amphotericin B liposomal overdose may include urinating less than usual or not at all.

What should I avoid while receiving amphotericin B liposomal (Ambisome)?

Amphotericin B liposomal may lower the blood cells that help your body fight other infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.

What other drugs will affect amphotericin B liposomal (Ambisome)?

Before receiving amphotericin B liposomal, tell your doctor if you are using any of the following drugs:

  • flucytosine (Ancobon);
  • digoxin (digitalis, Lanoxin, Lanoxicaps);
  • pentamidine (Nebupent, Pentam);
  • tacrolimus (Prograf);
  • muscle relaxers;
  • steroids (prednisone and others);
  • antifungal antibiotics such as clotrimazole (Mycelex Troche), fluconazole (Diflucan), ketoconazole (Nizoral), or itraconazole (Sporanox);
  • antibiotics such as capreomycin (Capastat), rifampin (Rifadin, Rimactane, Rifater), vancomycin (Vancocin, Vancoled);
  • antiviral medicines such as acyclovir (Zovirax), adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir); or
  • cancer medicine such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), plicamycin (Mithracin), streptozocin (Zanosar), or tretinoin (Vesanoid).

If you are using any of these drugs, you may not be able to receiveamphotericin B liposomal, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect amphotericin B liposomal. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has information about amphotericin B liposomal written for health professionals that you may read.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 1.04. Revision date: 12/15/2010.

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