In this Article

• What is amphotericin B liposomal (Ambisome)?
• What are the possible side effects of amphotericin B liposomal (Ambisome)?
• What is the most important information I should know about amphotericin B liposomal (Ambisome)?
• What should I discuss with my health care provider before receiving amphotericin B liposomal (Ambisome)?
• How is amphotericin B liposomal given (Ambisome)?
• What happens if I miss a dose (Ambisome)?
• What happens if I overdose (Ambisome)?
• What should I avoid while receiving amphotericin B liposomal (Ambisome)?
• What other drugs will affect amphotericin B liposomal (Ambisome)?
• Where can I get more information?

What should I discuss with my health care provider before receiving amphotericin B liposomal (Ambisome)?

Do not receive this medication if you are allergic to any formulation of amphotericin B (Abelcet, AmBisome, Amphotec, or Fungizone).

Before receiving amphotericin B liposomal, tell your doctor if you are allergic to any drugs, or if you have:

• kidney disease; or
• heart disease.

If you have any of these conditions, you may not be able to receive amphotericin B liposomal, or you may need dosage adjustments or special tests during treatment.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether amphotericin B liposomal passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is amphotericin B liposomal given (Ambisome)?

Amphotericin B liposomal is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting.

The medicine must be given slowly through an IV infusion, and can take up to 6 hours to complete.

While you are receiving your amphotericin B liposomal infusion, your caregivers will check your blood pressure, pulse, temperature, and lung function about every 30 minutes.

To be sure this medication is not causing harmful effects, your blood cells, kidney function, and liver function may also need to be tested.

Amphotericin B liposomal can have long-lasting effects on your body. Do not miss any follow-up visits to your doctor for blood or urine tests.