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Ambisome

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Ambisome

Ambisome Patient Information Including Side Effects

Brand Names: AmBisome

Generic Name: amphotericin B liposomal (Pronunciation: AM foe TER i sin B LYE poe SOE mal)

What is amphotericin B liposomal (Ambisome)?

Amphotericin B liposomal is an antifungal antibiotic that fights infections caused by fungus.

Amphotericin B liposomal is used to treat serious, life-threatening fungal infections including leishmaniasis, and a certain form of meningitis in people infected with HIV (human immunodeficiency virus). Amphotericin B liposomal is not for treating a minor fungal infection such as a yeast infection of the mouth, esophagus, or vagina.

Amphotericin B liposomal may also be used for purposes not listed in this medication guide.

What are the possible side effects of amphotericin B liposomal (Ambisome)?

Some people receiving a amphotericin B liposomal injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, hot or cold, or if you have a fast heartbeat, chest tightness, or trouble breathing.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • chest pain, pounding heartbeats or fluttering in your chest;
  • feeling light-headed or short of breath;
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, limp feeling);
  • loss of appetite, vomiting, urinating less than usual or not at all;
  • swelling, rapid weight gain;
  • pale skin, weakness, rapid heart rate, trouble concentrating; or
  • muscle pain, tenderness, or weakness (especially if you also have fever, unusual tiredness, and dark colored urine).

Less serious side effects may include:

  • chills;
  • nausea, diarrhea;
  • stomach pain;
  • headache;
  • flushing (warmth, redness, or tingly feeling);
  • sleep problems (insomnia); or
  • mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Ambisome (amphotericin b) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about amphotericin B liposomal (Ambisome)?

To make sure you can safely receive amphotericin B liposomal, tell your doctor if you have kidney or liver disease, or if you are allergic to amphotericin B (Abelcet, AmBisome, Amphotec, or Fungizone).

Amphotericin B liposomal may need to be given for up to several weeks or months, depending on the infection being treated.

Some people receiving a amphotericin B liposomal injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, hot or cold, or if you have a fast heartbeat, chest tightness, or trouble breathing.

Side Effects Centers
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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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