"Scientists at the National Institutes of Health report they have discovered in mouse studies that a small molecule released in the spinal cord triggers a process that is later experienced in the brain as the sensation of itch.
AMCINONIDE LOTION, 0.1%
NOT FOR OPHTHALMIC USE
FOR DERMATOLOGIC USE ONLY
The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and antipruritic agents.
Each gram of Amcinonide Lotion, 0.1% contains 1 mg of the active steroid amcinonide in a white, smooth, homogeneous, opaque emulsion composed of Benzyl Alcohol 1% (wt/wt) as preservative, Emulsifying Wax, Glycerin, Isopropyl Palmitate, Lactic Acid, Purified Water and Sorbitol Solution. In addition, contains Polyethylene Glycol 400. Sodium hydroxide may be used to adjust pH to approximately 4.4 during manufacture.Chemically, amcinonide is:
C28H35FO7 Molecular Weight 502.58
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-, (11β, 16α).
What are the possible side effects of amcinonide topical (Cyclocort)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing amcinonide topical through your skin, such as:
- blurred vision, or seeing halos around lights;
- mood changes;
- sleep problems (insomnia);
- weight gain, puffiness in your face; or
- muscle weakness, feeling tired.
Last reviewed on RxList: 9/15/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Amcinonide Lotion Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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