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Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Americaine (benzocaine)® Anesthetic Lubricant


AMERICAINE Anesthetic Lubricant contains benzocaine 20% with benzethonium chloride 0.1% as a preservative in a water soluble base of polyethylene glycol 300 and 3350.

Benzocaine, a local anesthetic, is chemically ethyl -aminobenzoate, C9H11NO2, with a molecular weight of 165.19. and has the following structual formula:

What are the possible side effects of benzocaine topical?

Benzocaine topical used in the mouth or throat may cause a life-threatening condition in which the amount of oxygen in your blood stream becomes dangerously low. This condition is called methemoglobinemia (met-HEEM-oh glo-bin-EE-mee-a) and it may occur after only one use of benzocaine or after several uses.

Signs and symptoms may occur within minutes or up to 2 hours after using benzocaine topical in the mouth or throat. GET EMERGENCY MEDICAL HELP IF YOU HAVE:

  • headache, tired feeling, confusion;
  • fast heart rate;
  • feeling light-headed or short of...

Read All Potential Side Effects and See Pictures of Americaine »

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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