"The U.S. Food and Drug Administration yesterday approved Obizur [Antihemophilic Factor (Recombinant), Porcine Sequence] for the treatment of bleeding episodes in adults with acquired hemophilia A (acquired Factor VIII [FVII] deficiency).
(aminocaproic acid) Oral Solution and Tablets
AMICAR (aminocaproic acid) is 6-aminohexanoic acid, which acts as an inhibitor of fibrinolysis.
Its chemical structure is:
AMICAR (aminocaproic acid) is soluble in water, acid, and alkaline solutions; it is sparingly soluble in methanol and practically insoluble in chloroform.
AMICAR (aminocaproic acid) Oral Solution for oral administration, contains 0.25 g/mL of aminocaproic acid with methylparaben 0.20%, propylparaben 0.05%, edetate disodium 0.30% as preservatives and the following inactive ingredients: sodium saccharin, sorbitol solution, citric acid anhydrous, natural and artificial raspberry flavor and an artificial bitterness modifier.
Each AMICAR (aminocaproic acid) Tablet, for oral administration contains 500 mg or 1000 mg of aminocaproic acid and the following inactive ingredients: povidone, crospovidone, stearic acid, and magnesium stearate.
What are the possible side effects of aminocaproic acid (Amicar)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using aminocaproic acid and call your doctor at once if you have a serious side effect such as:
- sudden numbness or weakness, especially on one side of the body;
- sudden headache, confusion, problems with vision, speech, or balance;
- sudden cough, rapid breathing, fast heart rate;
- pain or swelling in one or both legs;
- muscle pain, tenderness, or weakness with fever or flu...
What are the precautions when taking aminocaproic acid (Amicar)?
Before taking aminocaproic acid, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as paraben preservatives in the liquid product), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: bleeding of unknown cause, a certain bleeding condition (disseminated intravascular coagulation-DIC), a certain clotting problem (active intravascular clotting), a certain cause of blood in the urine (upper urinary tract bleeding).
Before using this medication, tell your doctor or pharmacist your medical...
Last reviewed on RxList: 3/11/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional Amicar Information
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