Aminosyn PF 7
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WebMD Health News
Reviewed by Arefa Cassoobhoy, MD, MPH
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Aminosyn PF 7% Sulfite Free
Aminosyn® -PF 7% (amino acid injection 7% pediatric formula)
AN AMINO ACID INJECTION - PEDIATRIC FORMULA
Flexible Plastic Container
Aminosyn®-PF 7%, Sulfite-Free, (an amino acid injection — pediatric formula) is a sterile, nonpyrogenic solution for intravenous infusion. Aminosyn®-PF 7% is oxygen sensitive. The formulation is described below:
An Amino Acid Injection — Pediatric Formula
Essential Amino Acids (mg/100 mL)
|* Amount cited is for lysine alone and does not include the acetate salt.|
Nonessential Amino Acids (mg/100 mL)
|Sodium (Na+) (mEq/L)||None|
|Potassium (K+) (mEq/L)||None|
|Chloride (Cl–) (mEq/L)||None|
|Acetate (C2H3O2–)a (mEq/L)||32.5|
|a From lysine acetate.|
|Protein Equivalent (Approx. grams/L)||70|
|Total Nitrogen (grams/L)||10.69|
|pH (range)||5.5 (5.0 to 6.5)|
The formulas for the individual amino acids present in Aminosyn-PF 7% are as follows:
Essential Amino Acids
|Lysine Acetate, USP||C6H14N2O2 • CH3COOH|
Nonessential Amino Acids
|L-Aspartic Acid|| C4H7NO4
|L-Glutamic Acid|| C5H9NO4
The flexible plastic container is fabricated from a specially formulated polyvinylchloride. Water can permeate from inside the container into the overwrap but not in amounts sufficient to affect the solution significantly.
Solutions in contact with the plastic container may leach out certain chemical components from the plastic in very small amounts; however, biological testing was supportive of the safety of the plastic container materials.
Exposure to temperatures above 25°C/77°F during transport and storage will lead to minor losses in moisture content. Higher temperatures lead to greater losses. It is unlikely that these minor losses will lead to clinically significant changes within the expiration period.
Last reviewed on RxList: 1/13/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional Aminosyn PF 7% Sulfite Free Information
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