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Medical Editor: John P. Cunha, DO, FACOEP
Amitiza (lubiprostone) is used to treat chronic constipation in adults. It is also used to treat irritable bowel syndrome in women with constipation as the main symptom. It is in a class of drugs known as chloride channel activators. Common side effects include nausea, diarrhea, gas, vomiting, dry mouth, runny nose, cough, fever, headache, dizziness, joint/back pain, or trouble sleeping.
To treat chronic idiopathic constipation, the recommended dose of Amitiza is 24 mcg twice daily orally with food and water. To treat irritable bowel syndrome with constipation, the recommended dose is 8 mcg twice daily orally with food and water. There may be other drugs that can affect Amitiza. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Amitiza is not recommended for use during pregnancy. Women should use birth control while taking this medication. It is unknown if this drug passes into breast milk, but it may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
Our Amitiza (lubiprostone) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Amitiza (lubiprostone) ® is indicated for the treatment of chronic idiopathic constipation in adults.
Amitiza (lubiprostone) is indicated for the treatment of irritable bowel syndrome with constipation (IBS-C) in women ≥ 18 years old.
Read the complete drug monograph for Amitiza »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Stop using lubiprostone and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have severe vomiting or diarrhea.
Less serious side effects are more likely to occur. Continue using lubiprostone and talk with your doctor if you have any of these less serious side effects:
Read the complete patient information for Amitiza »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
Read the complete consumer information for Amitiza »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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