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Amitiza Patient Information including How Should I Take

What should I discuss with my health care provider before taking lubiprostone (Amitiza)?

You should not use this medication if you have blockage in your digestive tract, or if you have severe diarrhea.

Before using this medication, tell your doctor if you have a history of hernia, gallstones, Crohn's disease, Hirschsprung's disease, impacted bowel movement, diverticulitis, polyps, or any other cause for obstruction in your gastrointestinal (digestive) system.

If you have any of these conditions, you may not be able to use lubiprostone or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C: This medication may be harmful to an unborn baby. Do not use lubiprostone without telling your doctor if you are pregnant. You may be asked to have a pregnancy test before you start taking lubiprostone. Tell your doctor if you become pregnant during treatment.

It is not known if lubiprostone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Lubiprostone should not be given to a child.

How should I take lubiprostone (Amitiza)?

Take lubiprostone exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Follow the directions on your prescription label.

Take lubiprostone with food.

Drink a full glass of water when you take this medication.

You may have tightness in your chest or feel short of breath within 1 hour after taking lubiprostone. This side effect should go away within 3 hours, but it may occur again when you take your next dose. Talk with your doctor if this side effect becomes bothersome.

Do not take lubiprostone if you have severe diarrhea. Call your doctor for instructions.

Store lubiprostone at room temperature away from moisture and heat.

Side Effects Centers

Amitiza - User Reviews

Amitiza User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Amitiza sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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