March 28, 2017
font size


Amlodipine

Brand Name: Norvasc

Generic Name: amlodipine

Drug Class: Calcium Channel Blockers; Antianginal Agents

What Is Amlodipine and How Does It Work?

Amlodipine a prescription medication that is used with or without other medications to treat high blood pressure. Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems. Amlodipine belongs to a class of drugs known as calcium channel blockers. It works by relaxing blood vessels so blood can flow more easily.

Amlodipine is also used to prevent certain types of chest pain (angina). It may help to increase your ability to exercise and decrease the frequency of angina attacks. It should not be used to treat attacks of chest pain when they occur. Use other medications (such as sublingual nitroglycerin) to relieve attacks of chest pain as directed by your doctor.

Amlodipine is available under the following different brand names: Norvasc.

Dosages of Amlodipine Should Be Given As Follows:

Adult and Pediatric Dosage Forms & Strengths

Tablets

  • 2.5 mg
  • 5 mg
  • 10 mg

Dosage Considerations

Hypertension (High Blood Pressure)

Adult

  • 5 mg/day orally initially; may be increased by 2.5 mg/day every 7-14 days; not to exceed 10 mg/day orally; maintenance: 5-10 mg/day orally

Pediatric

  • Children under 6 years: Safety and efficacy not established
  • Children 6 years and older: 2.5-5 mg/day orally

Geriatric

  • 2.5-5 mg/day orally initially; may be increased by 2.5 mg/day every 7-14 days; not to exceed 10 mg/day orally; maintenance: 5-10 mg/day orally

Coronary Artery Disease

Treatment of chronic stable angina and vasospastic angina (Prinzmetal or variant angina) and angiographically documented coronary artery disease (CAD) in patients without heart failure or ejection fraction (EF) less than 40%

Adult

  • 5-10 mg/day orally initially; maintenance: 10 mg/day orally

Geriatric

  • 2.5-10 mg/day orally initially; maintenance: 10 mg/day orally

Angina

Adult

  • 5-10 mg/day orally; maintenance: 10 mg/day orally

Geriatric

  • 2.5-10 mg/day orally; maintenance: 10 mg/day

Dosage Modifications

Hepatic insufficiency: Consider starting with 2.5 mg/day orally

Severe hepatic impairment: Titrate slowly

Dosing Considerations

Also given in combination with benazepril (Lotrel), atorvastatin (Caduet), olmesartan (Azor), telmisartan (Twynsta), and valsartan (Exforge)

Geriatric

  • Start dosing at low end of dosing range; elderly patients have greater frequency of decreased renal, hepatic or cardiac function
Medically Reviewed by a Doctor on 3/10/2017



Hypertension

Get tips on handling your hypertension.

advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations