home > drugs a-z list > amphadase (hyaluronidase inj) drug center > amphadase (hyaluronidase inj) drug - consumer uses and warnings

Amphadase (hyaluronidase inj) is a preparation of purified bovine testicular hyaluronidase, a protein enzyme. The exact chemical structure of this enzyme is unknown. However, the amino acid sequence for the primary structure of the enzyme has been deduced from the sequence of purified peptides.

Amphadase (hyaluronidase injection) is supplied as a sterile, colorless, ready for use solution. Each vial contains 150 USP units of hyaluronidase per mL with 8.5 mg sodium chloride, 1 mg edetate disodium, 0.4 mg calcium chloride, monobasic sodium phosphate buffer, and not more than 0.1 mg thimerosal (mercury derivative).

The ready for use solution is clear and colorless with an approximate pH of 6.8 and an osmolality of 295 to 355 mOsm.

Last reviewed on RxList: 1/29/2009
This monograph has been modified to include the generic and brand name in many instances.