Ampyra (Dalfampridine Extended-Release Tablets) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 24, 2012

Ampyra

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AMPYRA™
(dalfampridine) Extended Release Tablets, for Oral Use

DRUG DESCRIPTION

AMPYRA (dalfampridine) is a potassium channel blocker, available in a 10 mg tablet strength. Each tablet contains 10 mg dalfampridine, formulated as an extended release tablet for twice-daily oral administration. Dalfampridine is also known by its chemical name, 4-aminopyridine, with the following structure:

AMPYRA (dalfampridine) Structural Formula Illustration

AMPYRA (dalfampridine) Extended Release tablets are available in a 10 mg strength and are a white to off-white, biconvex, oval shaped, film-coated, nonscored tablet with flat edge, debossed with “A10” on one side, containing 10 mg of dalfampridine. Inactive ingredients consist of colloidal silicon dioxide, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, and titanium dioxide.

Dalfampridine is a fine white powder with a molecular weight of 94.1, CAS 504-24-5 and a molecular formula of C5H6N2. At ambient conditions, dalfampridine is soluble in water, methanol, acetone, tetrahydrofuran, isopropanol, acetonitrile, N,N-dimethylformamide, dimethylsulfoxide, and ethanol.

Last reviewed on RxList: 2/9/2010
This monograph has been modified to include the generic and brand name in many instances.