In this Article

• What is aliskiren, amlodipine, and hydrochlorothiazide (Amturnide)?
• What are the possible side effects of aliskiren, amlodipine, and hydrochlorothiazide (Amturnide)?
• What is the most important information I should know about aliskiren, amlodipine, and hydrochlorothiazide (Amturnide)?
• What should I discuss with my healthcare provider before taking aliskiren, amlodipine, and hydrochlorothiazide (Amturnide)?
• How should I take aliskiren, amlodipine, and hydrochlorothiazide (Amturnide)?
• What happens if I miss a dose (Amturnide)?
• What happens if I overdose (Amturnide)?
• What should I avoid while taking aliskiren, amlodipine, and hydrochlorothiazide (Amturnide)?
• What other drugs will affect aliskiren, amlodipine, and hydrochlorothiazide (Amturnide)?
• Where can I get more information?

What should I discuss with my healthcare provider before taking aliskiren, amlodipine, and hydrochlorothiazide (Amturnide)?

You should not take this medication if you are allergic to aliskiren (Tekturna, Tekamlo), amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tribenzor, Twynsta), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Vaseretic, Zestoretic, and many others), or sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, and others).

You should not take aliskiren, amlodipine, and hydrochlorothiazide if you have severe kidney disease or are unable to urinate, or if you are also taking itraconazole (Sporanox) or cyclosporine (Gengraf, Neoral, Sandimmune).

To make sure you can safely take aliskiren, amlodipine, and hydrochlorothiazide, tell your doctor if you have any of these other conditions:

• kidney disease (or if you are on dialysis);
• liver disease;
• congestive heart failure;
• angina (chest pain);
• glaucoma;
• systemic lupus erythematosus (SLE);
• asthma;
• coronary artery disease (hardened arteries);
• an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);
• if you are allergic to penicillin;
• if you are on a low-salt diet; or
• if you have ever had an allergic reaction to a blood pressure medication.

FDA pregnancy category D. Do not use aliskiren, amlodipine, and hydrochlorothiazide if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. This medication can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking aliskiren, amlodipine, and hydrochlorothiazide.

It is not known whether this medication passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking aliskiren, amlodipine, and hydrochlorothiazide.

How should I take aliskiren, amlodipine, and hydrochlorothiazide (Amturnide)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Your chest pain may become worse when you first start taking the medicine or when your dose is increased. Call your doctor if your chest pain is severe or ongoing.

Aliskiren, amlodipine, and hydrochlorothiazide may be taken with or without food, but take it the same way each time.

While using aliskiren, amlodipine, and hydrochlorothiazide, you may need blood tests at your doctor's office. Your blood pressure will need to be checked often. Visit your doctor regularly.

If you need surgery, tell the surgeon ahead of time that you are using aliskiren, amlodipine, and hydrochlorothiazide.

Conditions that may cause very low blood pressure include: vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low salt diet, or taking diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you should drink while taking aliskiren, amlodipine, and hydrochlorothiazide. Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store in the original container at room temperature, away from moisture and heat.